Research progress of pyroptosis in sepsis / 中华危重病急救医学
Chinese Critical Care Medicine
; (12): 498-500, 2019.
Article
in Zh
| WPRIM
| ID: wpr-754001
Responsible library:
WPRO
ABSTRACT
Sepsis is an organ dysfunction syndrome caused by an abnormal host immune response because of infection. Pyroptosis is a newly discovered programmed cell death relies on caspase-1, caspase-11, caspase-4, caspase-5 and is characterized by the release of inflammatory cytokines interleukin-1β (IL-1β) and IL-18. The exploration of the molecular mechanisms of pyroptosis and the correlation between pyroptosis and sepsis can provide new ideas and new targets for the treatment of sepsis.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Critical Care Medicine
Year:
2019
Document type:
Article